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Opposing effects of cohesin and transcription on CTCF organization revealed by super-resolution imaging
CTCF and cohesin play critical roles in organizing mammalian genomes into topologically associating domains (TADs). Here, by combining genetic engineering with quantitative super-resolution Stimulated Emission Depletion (STED) microscopy, we demonstrate that in living cells CTCF forms clusters typic...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7725164/ https://ncbi.nlm.nih.gov/pubmed/33091336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.001 |
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