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Large‐scale survey and database of high affinity ligands for peptide recognition modules

Many proteins involved in signal transduction contain peptide recognition modules (PRMs) that recognize short linear motifs (SLiMs) within their interaction partners. Here, we used large‐scale peptide‐phage display methods to derive optimal ligands for 163 unique PRMs representing 79 distinct struct...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Syst Biol
Hauptverfasser: Teyra, Joan, Kelil, Abdellali, Jain, Shobhit, Helmy, Mohamed, Jajodia, Raghav, Hooda, Yogesh, Gu, Jun, D’Cruz, Akshay A, Nicholson, Sandra E, Min, Jinrong, Sudol, Marius, Kim, Philip M, Bader, Gary D, Sidhu, Sachdev S
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724964/
https://ncbi.nlm.nih.gov/pubmed/33438817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20199310
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