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CellectSeq: In silico discovery of antibodies targeting integral membrane proteins combining in situ selections and next-generation sequencing

Synthetic antibody (Ab) technologies are efficient and cost-effective platforms for the generation of monoclonal Abs against human antigens. Yet, they typically depend on purified proteins, which exclude integral membrane proteins that require the lipid bilayers to support their native structure and...

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Dades bibliogràfiques
Publicat a:Commun Biol
Autors principals: Kelil, Abdellali, Gallo, Eugenio, Banerjee, Sunandan, Adams, Jarrett J., Sidhu, Sachdev S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115320/
https://ncbi.nlm.nih.gov/pubmed/33980972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02066-5
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