Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes

Circular RNAs (circRNAs) are stable RNA molecules that can drive cancer through interactions with microRNAs and proteins and by the expression of circRNA encoded peptides. The aim of the study was to define the circRNA landscape and potential impact in T-cell acute lymphoblastic leukemia (T-ALL). An...

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Veröffentlicht in:Blood Adv
Hauptverfasser: Buratin, Alessia, Paganin, Maddalena, Gaffo, Enrico, Dal Molin, Anna, Roels, Juliette, Germano, Giuseppe, Siddi, Maria Teresa, Serafin, Valentina, De Decker, Matthias, Gachet, Stéphanie, Durinck, Kaat, Speleman, Frank, Taghon, Tom, te Kronnie, Geertruij, Van Vlierberghe, Pieter, Bortoluzzi, Stefania
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724907/
https://ncbi.nlm.nih.gov/pubmed/33259601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002337
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