CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out

Juvenile myelomonocytic leukemia (JMML), a rare myelodysplastic/myeloproliferative neoplasm of early childhood, is characterized by clonal growth of RAS signaling addicted stem cells. JMML subtypes are defined by specific RAS pathway mutations and display distinct gene, microRNA (miRNA) and long non...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Dal Molin, Anna, Hofmans, Mattias, Gaffo, Enrico, Buratin, Alessia, Cavé, Hélène, Flotho, Christian, de Haas, Valerie, Niemeyer, Charlotte M., Stary, Jan, Van Vlierberghe, Pieter, Philippé, Jan, De Moerloose, Barbara, te Kronnie, Geertruij, Bresolin, Silvia, Lammens, Tim, Bortoluzzi, Stefania
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815690/
https://ncbi.nlm.nih.gov/pubmed/33490078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.613540
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