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CircRNAs Are Here to Stay: A Perspective on the MLL Recombinome
Chromosomal translocations harbored by cancer genomes are important oncogenic drivers. In MLL rearranged acute leukemia (MLLre) MLL/KMT2A fuses with over 90 partner genes. Mechanistic studies provided clues of MLL fusion protein leukemogenic potential, but models failed to fully recapitulate the dis...
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| Publicado no: | Front Genet |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6382020/ https://ncbi.nlm.nih.gov/pubmed/30815012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00088 |
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