CircRNAs Are Here to Stay: A Perspective on the MLL Recombinome

Chromosomal translocations harbored by cancer genomes are important oncogenic drivers. In MLL rearranged acute leukemia (MLLre) MLL/KMT2A fuses with over 90 partner genes. Mechanistic studies provided clues of MLL fusion protein leukemogenic potential, but models failed to fully recapitulate the dis...

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Udgivet i:Front Genet
Main Authors: Dal Molin, Anna, Bresolin, Silvia, Gaffo, Enrico, Tretti, Caterina, Boldrin, Elena, Meyer, Lueder H., Guglielmelli, Paola, Vannucchi, Alessandro M., te Kronnie, Geertruij, Bortoluzzi, Stefania
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382020/
https://ncbi.nlm.nih.gov/pubmed/30815012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00088
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