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The Notch Ligand Jagged1 Is Required for the Formation, Maintenance, and Survival of Hensen's Cells in the Mouse Cochlea

During cochlear development, the Notch ligand JAGGED 1 (JAG1) plays an important role in the specification of the prosensory region, which gives rise to sound-sensing hair cells and neighboring supporting cells (SCs). While JAG1's expression is maintained in SCs through adulthood, the function...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chrysostomou, Elena, Zhou, Luyi, Darcy, Yuanzhao L., Graves, Kaley A., Doetzlhofer, Angelika, Cox, Brandon C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724135/
https://ncbi.nlm.nih.gov/pubmed/33127852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1192-20.2020
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