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Induction of Noonan syndrome-specific human-induced pluripotent stem cells under serum-, feeder-, and integration-free conditions

Noonan syndrome is an autosomal dominant developmental disorder. Although it is relatively common, and its phenotypical variability is well documented, its pathophysiology is not fully understood. Previously, with the aim of revealing the pathogenesis of genetic disorders, we reported the induction...

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Bibliographische Detailangaben
Veröffentlicht in:In Vitro Cell Dev Biol Anim
Hauptverfasser: Hamada, Atsuko, Akagi, Eri, Obayashi, Fumitaka, Yamasaki, Sachiko, Koizumi, Koichi, Ohtaka, Manami, Nishimura, Ken, Nakanishi, Mahito, Toratani, Shigeaki, Okamoto, Tetsuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723931/
https://ncbi.nlm.nih.gov/pubmed/33140329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-020-00515-9
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