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Induction of Noonan syndrome-specific human-induced pluripotent stem cells under serum-, feeder-, and integration-free conditions

Noonan syndrome is an autosomal dominant developmental disorder. Although it is relatively common, and its phenotypical variability is well documented, its pathophysiology is not fully understood. Previously, with the aim of revealing the pathogenesis of genetic disorders, we reported the induction...

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Detalhes bibliográficos
Publicado no:In Vitro Cell Dev Biol Anim
Main Authors: Hamada, Atsuko, Akagi, Eri, Obayashi, Fumitaka, Yamasaki, Sachiko, Koizumi, Koichi, Ohtaka, Manami, Nishimura, Ken, Nakanishi, Mahito, Toratani, Shigeaki, Okamoto, Tetsuji
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723931/
https://ncbi.nlm.nih.gov/pubmed/33140329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-020-00515-9
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