Association of clock-like mutational signature with immune checkpoint inhibitor outcome in patients with melanoma and NSCLC

Immune checkpoint inhibitor (ICI) therapy has achieved remarkable clinical benefit in melanoma and non-small cell lung cancer (NSCLC). Tumor mutational signatures are the fingerprints of endogenous and exogenous factors that have acted throughout tumorigenesis and heterogeneity; however, their assoc...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Chong, Wei, Wang, Zhe, Shang, Liang, Jia, Shengtao, Liu, Jin, Fang, Zhen, Du, Fengying, Wu, Hao, Liu, Yang, Chen, Yang, Chen, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723771/
https://ncbi.nlm.nih.gov/pubmed/33335795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.033
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