Amyloid-beta uptake by blood monocytes is reduced with ageing and Alzheimer’s disease

Deficits in the clearance of amyloid β-protein (Aβ) play a pivotal role in the pathogenesis of sporadic Alzheimer’s disease (AD). The roles of blood monocytes in the development of AD remain unclear. In this study, we sought to investigate the alterations in the Aβ phagocytosis function of periphera...

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Publicado en:Transl Psychiatry
Main Authors: Chen, Si-Han, Tian, Ding-Yuan, Shen, Ying-Ying, Cheng, Yuan, Fan, Dong-Yu, Sun, Hao-Lun, He, Chen-Yang, Sun, Pu-Yang, Bu, Xian-Le, Zeng, Fan, Liu, Juan, Deng, Juan, Xu, Zhi-Qiang, Chen, Yang, Wang, Yan-Jiang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722845/
https://ncbi.nlm.nih.gov/pubmed/33293506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01113-9
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