Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

The transmembrane protein CD33 is a sialic acid-binding immunoglobulin-like lectin that regulates innate immunity but has no known functions in the brain. We have previously shown that the CD33 gene is a risk factor for Alzheimer’s disease (AD). Here, we observed increased expression of CD33 in micr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Griciuc, Ana, Serrano-Pozo, Alberto, Parrado, Antonio R., Lesinski, Andrea N., Asselin, Caroline N., Mullin, Kristina, Hooli, Basavaraj, Choi, Se Hoon, Hyman, Bradley T., Tanzi, Rudolph E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706457/
https://ncbi.nlm.nih.gov/pubmed/23623698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.04.014
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन