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Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration. However, the mechanism of movement is unknown. We hypothesized t...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Cray, Paul, Sheahan, Breanna J., Cortes, Jocsa E., Dekaney, Christopher M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722747/
https://ncbi.nlm.nih.gov/pubmed/33293626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78473-1
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