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Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration. However, the mechanism of movement is unknown. We hypothesized t...

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Publicado en:Sci Rep
Autores principales: Cray, Paul, Sheahan, Breanna J., Cortes, Jocsa E., Dekaney, Christopher M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722747/
https://ncbi.nlm.nih.gov/pubmed/33293626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78473-1
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