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Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration. However, the mechanism of movement is unknown. We hypothesized t...

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Publicat a:Sci Rep
Autors principals: Cray, Paul, Sheahan, Breanna J., Cortes, Jocsa E., Dekaney, Christopher M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722747/
https://ncbi.nlm.nih.gov/pubmed/33293626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78473-1
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