Prefrontal cortex infusion of beta‐hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant‐like effects in a rodent model of depression

AIMS: Neuroinflammation is deeply related to the pathophysiology of depression. Beta‐hydroxybutyrate (BHB), which is an endogenous ketone body, exerts anti‐inflammatory effects, and peripheral administration of BHB induces antidepressant effects in an animal model of depression; however, it is uncle...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Neuropsychopharmacol Rep
Auteurs principaux: Kajitani, Naofumi, Iwata, Masaaki, Miura, Akihiko, Tsunetomi, Kyohei, Yamanashi, Takehiko, Matsuo, Ryoichi, Nishiguchi, Tsuyoshi, Fukuda, Saki, Nagata, Mayu, Shibushita, Midori, Yamauchi, Takahira, Pu, Shenghong, Shirayama, Yukihiko, Watanabe, Ken, Kaneko, Koichi
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722664/
https://ncbi.nlm.nih.gov/pubmed/32125791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/npr2.12099
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires