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Prefrontal cortex infusion of beta‐hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant‐like effects in a rodent model of depression

AIMS: Neuroinflammation is deeply related to the pathophysiology of depression. Beta‐hydroxybutyrate (BHB), which is an endogenous ketone body, exerts anti‐inflammatory effects, and peripheral administration of BHB induces antidepressant effects in an animal model of depression; however, it is uncle...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuropsychopharmacol Rep
Päätekijät: Kajitani, Naofumi, Iwata, Masaaki, Miura, Akihiko, Tsunetomi, Kyohei, Yamanashi, Takehiko, Matsuo, Ryoichi, Nishiguchi, Tsuyoshi, Fukuda, Saki, Nagata, Mayu, Shibushita, Midori, Yamauchi, Takahira, Pu, Shenghong, Shirayama, Yukihiko, Watanabe, Ken, Kaneko, Koichi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722664/
https://ncbi.nlm.nih.gov/pubmed/32125791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/npr2.12099
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