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Prodrug strategies for improved efficacy of nucleoside antiviral inhibitors

PURPOSE OF REVIEW: This review focuses on the chemical and pharmacological rationale behind the development of nucleoside antiviral prodrugs (NAPs). RECENT FINDINGS: Highly efficacious NAPs have been developed that extend and improve the quality of lives of individuals infected with HIV and hepatiti...

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Detalhes bibliográficos
Publicado no:Curr Opin HIV AIDS
Main Authors: Hurwitz, Selwyn J., Schinazi, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722247/
https://ncbi.nlm.nih.gov/pubmed/24100876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000007
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