Llwytho...

An injectable hydrogel-formulated inhibitor of prolyl-4-hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis

The hypoxia-inducible factor 1α (HIF-1α) is critically involved in tissue regeneration. Hence, the pharmacological prevention of HIF-1α degradation by prolyl hydroxylase (PHD) under normoxic conditions is emerging as a promising option in regenerative medicine. Using a mouse model of ligature-induce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Nagai, Kosuke, Ideguchi, Hidetaka, Kajikawa, Tetsuhiro, Li, Xiaofei, Chavakis, Triantafyllos, Cheng, Jing, Messersmith, Phillip B., Heber-Katz, Ellen, Hajishengallis, George
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722135/
https://ncbi.nlm.nih.gov/pubmed/32812255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001248R
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