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Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases

G protein-coupled receptors (GPCRs) play critical roles in transmitting a variety of extracellular signals into the cells and regulate diverse physiological functions. Naturally occurring mutations that result in dysfunctions of GPCRs have been known as the causes of numerous diseases. Significant p...

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Bibliografische gegevens
Gepubliceerd in:Biochim Biophys Acta Mol Basis Dis
Hoofdauteurs: Yang, Li-Kun, Hou, Zhi-Shuai, Tao, Ya-Xiong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722056/
https://ncbi.nlm.nih.gov/pubmed/32949766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2020.165973
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