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Quantifying the influence of mutation detection on tumour subclonal reconstruction
Whole-genome sequencing can be used to estimate subclonal populations in tumours and this intra-tumoural heterogeneity is linked to clinical outcomes. Many algorithms have been developed for subclonal reconstruction, but their variabilities and consistencies are largely unknown. We evaluate sixteen...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7721877/ https://ncbi.nlm.nih.gov/pubmed/33288765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20055-w |
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