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Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia
The bioactive vitamin D(3), 1α,25(OH)(2)D(3), plays a central role in calcium homeostasis by controlling the activity of the vitamin D receptor (VDR) in various tissues. Hypercalcemia secondary to high circulating levels of vitamin D(3) leads to hypercalciuria, nephrocalcinosis and renal dysfunction...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7721737/ https://ncbi.nlm.nih.gov/pubmed/33288743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20069-4 |
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