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Hydration and Dynamics of Full-Length Tau Amyloid Fibrils Investigated by Solid-State NMR

The microtubule-associated protein tau aggregates into distinct neurofibrillary tangles in brains afflicted with multiple neurodegenerative diseases such as Alzheimer’s disease and corticobasal degeneration (CBD). The mechanism of tau misfolding and aggregation is poorly understood. Determining the...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Dregni, Aurelio J., Duan, Pu, Hong, Mei
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720860/
https://ncbi.nlm.nih.gov/pubmed/32453948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00342
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