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Hydration and Dynamics of Full-Length Tau Amyloid Fibrils Investigated by Solid-State NMR

The microtubule-associated protein tau aggregates into distinct neurofibrillary tangles in brains afflicted with multiple neurodegenerative diseases such as Alzheimer’s disease and corticobasal degeneration (CBD). The mechanism of tau misfolding and aggregation is poorly understood. Determining the...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Dregni, Aurelio J., Duan, Pu, Hong, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720860/
https://ncbi.nlm.nih.gov/pubmed/32453948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00342
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