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MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features

The microtubule-associated protein tau (MAPT) H1 haplotype is the strongest genetic risk factor for corticobasal degeneration (CBD). However, the specific H1 subhaplotype association is not well defined, and it is not clear whether any MAPT haplotypes influence severity of tau pathology or clinical...

詳細記述

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書誌詳細
出版年:Acta Neuropathol Commun
主要な著者: Valentino, Rebecca R., Koga, Shunsuke, Walton, Ronald L., Soto-Beasley, Alexandra I., Kouri, Naomi, DeTure, Michael A., Murray, Melissa E., Johnson, Patrick W., Petersen, Ronald C., Boeve, Bradley F., Uitti, Ryan J., Wszolek, Zbigniew K., Dickson, Dennis W., Ross, Owen A., Heckman, Michael G.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720600/
https://ncbi.nlm.nih.gov/pubmed/33287913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01097-z
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