Associations of mitochondrial genomic variation with corticobasal degeneration, progressive supranuclear palsy, and neuropathological tau measures

Mitochondrial health is important in ageing and dysfunctional oxidative phosphorylation (OXPHOS) accelerates ageing and influences neurodegeneration. Mitochondrial DNA (mtDNA) codes for vital OXPHOS subunits and mtDNA background has been associated with neurodegeneration; however, no study has chara...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Valentino, Rebecca R., Tamvaka, Nikoleta, Heckman, Michael G., Johnson, Patrick W., Soto-Beasley, Alexandra I., Walton, Ronald L., Koga, Shunsuke, Uitti, Ryan J., Wszolek, Zbigniew K., Dickson, Dennis W., Ross, Owen A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495714/
https://ncbi.nlm.nih.gov/pubmed/32943110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01035-z
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