The intracellular Ca(2+) release channel TRPML1 regulates lower urinary tract smooth muscle contractility

TRPML1 (transient receptor potential mucolipin 1) is a Ca(2+)-permeable, nonselective cation channel that is predominantly localized to the membranes of late endosomes and lysosomes (LELs). Intracellular release of Ca(2+) through TRPML1 is thought to be pivotal for maintenance of intravesicular acid...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Griffin, Caoimhin S., Alvarado, Michael G., Yamasaki, Evan, Drumm, Bernard T., Krishnan, Vivek, Ali, Sher, Nagle, Eleanor M., Sanders, Kenton M., Earley, Scott
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720193/
https://ncbi.nlm.nih.gov/pubmed/33199609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016959117
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