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The intracellular Ca(2+) release channel TRPML1 regulates lower urinary tract smooth muscle contractility
TRPML1 (transient receptor potential mucolipin 1) is a Ca(2+)-permeable, nonselective cation channel that is predominantly localized to the membranes of late endosomes and lysosomes (LELs). Intracellular release of Ca(2+) through TRPML1 is thought to be pivotal for maintenance of intravesicular acid...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720193/ https://ncbi.nlm.nih.gov/pubmed/33199609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016959117 |
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