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An S/T motif controls reversible oligomerization of the Hsp40 chaperone DNAJB6b through subtle reorganization of a β sheet backbone

Chaperone oligomerization is often a key aspect of their function. Irrespective of whether chaperone oligomers act as reservoirs for active monomers or exhibit a chaperoning function themselves, understanding the mechanism of oligomerization will further our understanding of how chaperones maintain...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Karamanos, Theodoros K., Tugarinov, Vitali, Clore, G. Marius
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720152/
https://ncbi.nlm.nih.gov/pubmed/33199640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020306117
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