Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics

Erythropoiesis is the most robust cellular differentiation and proliferation system, with a production of ∼2 × 10(11) cells per day. In this fine-tuned process, the hematopoietic stem cells (HSCs) generate erythroid progenitors, which proliferate and mature into erythrocytes. During erythropoiesis,...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Gonzalez-Ibanez, Alvaro M., Ruiz, Lina M., Jensen, Erik, Echeverria, Cesar A., Romero, Valentina, Stiles, Linsey, Shirihai, Orian S., Elorza, Alvaro A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719720/
https://ncbi.nlm.nih.gov/pubmed/33330472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.592035
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