Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Accumulation of depolarized mitochondria within β-cells has been associated with oxidative damage and development of diabetes. To determine the source and fate of depolarized mitochondria, individual mitochondria were photolabeled and tracked through fusion and fission. Mitochondria were found to go...

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Main Authors: Twig, Gilad, Elorza, Alvaro, Molina, Anthony J A, Mohamed, Hibo, Wikstrom, Jakob D, Walzer, Gil, Stiles, Linsey, Haigh, Sarah E, Katz, Steve, Las, Guy, Alroy, Joseph, Wu, Min, Py, Bénédicte F, Yuan, Junying, Deeney, Jude T, Corkey, Barbara E, Shirihai, Orian S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234339/
https://ncbi.nlm.nih.gov/pubmed/18200046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601963
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