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TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2
Tripartite motif (TRIM) family proteins are important effectors of innate immunity against viral infections. Here we identified TRIM35 as a regulator of TRAF3 activation. Deficiency in or inhibition of TRIM35 suppressed the production of type I interferon (IFN) in response to viral infection. Trim35...
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| 出版年: | Protein Cell |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Higher Education Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7719147/ https://ncbi.nlm.nih.gov/pubmed/32562145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-020-00734-6 |
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