Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission

Posttranslational modifications, such as SUMOylation, play specific roles in the life cycle of invading pathogens. However, the effect of SUMOylation on the adaptation, pathogenesis, and transmission of influenza A virus (IAV) remains largely unknown. Here, we found that a conserved lysine residue a...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Li, Junping, Liang, Libin, Jiang, Li, Wang, Qian, Wen, Xia, Zhao, Yuhui, Cui, Pengfei, Zhang, Yaping, Wang, Guangwen, Li, Qibing, Deng, Guohua, Shi, Jianzhong, Tian, Guobin, Zeng, Xianying, Jiang, Yongping, Liu, Liling, Chen, Hualan, Li, Chengjun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904188/
https://ncbi.nlm.nih.gov/pubmed/33571308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009336
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