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Alleviating cellular oxidative stress through treatment with superoxide-triggered persulfide prodrugs

Overproduction of superoxide anion (O(2)∙(−)), the primary cellular reactive oxygen species (ROS), is implicated in various human diseases. To reduce cellular oxidative stress caused by overproduction of superoxide, we developed a compound that reacts with O(2)∙(−) to release a persulfide (RSSH), a...

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Bibliografiset tiedot
Julkaisussa:Angew Chem Int Ed Engl
Päätekijät: Wang, Yin, Dillon, Kearsley M., Li, Zhao, Winckler, Ethan W., Matson, John B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719095/
https://ncbi.nlm.nih.gov/pubmed/32592216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006656
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