Targeted delivery of persulfides to the gut: Effects on the microbiome

Persulfides (R-SSH) have been hypothesized as potent redox modulators and signaling compounds. Reported here is the synthesis, characterization, and in vivo evaluation of a persulfide donor that releases N-acetyl cysteine persulfide (NAC-SSH) in response to the prokaryote-specific enzyme nitroreduct...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Dillon, Kearsley M., Morrison, Holly A., Powell, Chadwick R., Carrazzone, Ryan J., Ringel-Scaia, Veronica M., Winckler, Ethan W., Council-Troche, R. McAlister, Allen, Irving C., Matson, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967250/
https://ncbi.nlm.nih.gov/pubmed/33511734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202014052
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