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Alleviating cellular oxidative stress through treatment with superoxide-triggered persulfide prodrugs
Overproduction of superoxide anion (O(2)∙(−)), the primary cellular reactive oxygen species (ROS), is implicated in various human diseases. To reduce cellular oxidative stress caused by overproduction of superoxide, we developed a compound that reacts with O(2)∙(−) to release a persulfide (RSSH), a...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7719095/ https://ncbi.nlm.nih.gov/pubmed/32592216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006656 |
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