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Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission

Dynamin‐related protein 1 (Drp1) is a cytosolic protein responsible for mitochondrial fission and is essential in the initiation and development of several human diseases, including cancer. However, the regulation of Drp1, especially of its ubiquitination, remains unclear. In this study, we report t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Shi, Le, Liu, Jing, Peng, Yunhua, Zhang, Jinfang, Dai, Xiangpeng, Zhang, Shuangxi, Wang, Yongyao, Liu, Jiankang, Long, Jiangang
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718948/
https://ncbi.nlm.nih.gov/pubmed/33070427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12825
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