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Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission

Dynamin‐related protein 1 (Drp1) is a cytosolic protein responsible for mitochondrial fission and is essential in the initiation and development of several human diseases, including cancer. However, the regulation of Drp1, especially of its ubiquitination, remains unclear. In this study, we report t...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Shi, Le, Liu, Jing, Peng, Yunhua, Zhang, Jinfang, Dai, Xiangpeng, Zhang, Shuangxi, Wang, Yongyao, Liu, Jiankang, Long, Jiangang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718948/
https://ncbi.nlm.nih.gov/pubmed/33070427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12825
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