Silencing of the Long Noncoding RNA MYCNOS1 Suppresses Activity of MYCN-Amplified Retinoblastoma Without RB1 Mutation

PURPOSE: MYCNOS (MYCN opposite strand) is co-amplified with MYCN in pediatric cancers, including retinoblastoma. MYCNOS encodes several RNA variants whose functions have not been elucidated in retinoblastoma. Thus, we attempted to identify MYCNOS variants in retinoblastoma and aimed to decipher the...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Saengwimol, Duangporn, Chittavanich, Pamorn, Laosillapacharoen, Natanan, Srimongkol, Atthapol, Chaitankar, Vijender, Rojanaporn, Duangnate, Aroonroch, Rangsima, Suktitipat, Bhoom, Saisawang, Chonticha, Svasti, Saovaros, Hongeng, Suradej, Kaewkhaw, Rossukon
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2020
Témata:
Retina
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718827/
https://ncbi.nlm.nih.gov/pubmed/33270844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.14.8
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