Silencing of the Long Noncoding RNA MYCNOS1 Suppresses Activity of MYCN-Amplified Retinoblastoma Without RB1 Mutation

PURPOSE: MYCNOS (MYCN opposite strand) is co-amplified with MYCN in pediatric cancers, including retinoblastoma. MYCNOS encodes several RNA variants whose functions have not been elucidated in retinoblastoma. Thus, we attempted to identify MYCNOS variants in retinoblastoma and aimed to decipher the...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Saengwimol, Duangporn, Chittavanich, Pamorn, Laosillapacharoen, Natanan, Srimongkol, Atthapol, Chaitankar, Vijender, Rojanaporn, Duangnate, Aroonroch, Rangsima, Suktitipat, Bhoom, Saisawang, Chonticha, Svasti, Saovaros, Hongeng, Suradej, Kaewkhaw, Rossukon
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2020
Assuntos:
Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718827/
https://ncbi.nlm.nih.gov/pubmed/33270844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.14.8
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