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Retinoblastoma: Etiology, Modeling, and Treatment

Retinoblastoma is a retinal cancer that is initiated in response to biallelic loss of RB1 in almost all cases, together with other genetic/epigenetic changes culminating in the development of cancer. RB1 deficiency makes the retinoblastoma cell-of-origin extremely susceptible to cancerous transforma...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kaewkhaw, Rossukon, Rojanaporn, Duangnate
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465685/
https://ncbi.nlm.nih.gov/pubmed/32824373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082304
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