A three-dimensional organoid model recapitulates tumorigenic aspects and drug responses of advanced human retinoblastoma

Persistent or recurrent retinoblastoma (RB) is associated with the presence of vitreous or/and subretinal seeds in advanced RB and represents a major cause of therapeutic failure. This necessitates the development of novel therapies and thus requires a model of advanced RB for testing candidate ther...

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Publicado no:Sci Rep
Main Authors: Saengwimol, Duangporn, Rojanaporn, Duangnate, Chaitankar, Vijender, Chittavanich, Pamorn, Aroonroch, Rangsima, Boontawon, Tatpong, Thammachote, Weerin, Jinawath, Natini, Hongeng, Suradej, Kaewkhaw, Rossukon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199308/
https://ncbi.nlm.nih.gov/pubmed/30353124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34037-y
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