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Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology
PURPOSE: Vitronectin, a cell adhesion and spreading factor, is suspected to play a role in the pathogenesis of age-related macular degeneration (AMD), as it is a major component of AMD-specific extracellular deposits (e.g., soft drusen, subretinal drusenoid deposits). The present study addressed the...
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| Publicat a: | Invest Ophthalmol Vis Sci |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7718807/ https://ncbi.nlm.nih.gov/pubmed/33259607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.14.2 |
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