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Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology

PURPOSE: Vitronectin, a cell adhesion and spreading factor, is suspected to play a role in the pathogenesis of age-related macular degeneration (AMD), as it is a major component of AMD-specific extracellular deposits (e.g., soft drusen, subretinal drusenoid deposits). The present study addressed the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Invest Ophthalmol Vis Sci
मुख्य लेखकों: Biasella, Fabiola, Plössl, Karolina, Karl, Claudia, Weber, Bernhard H. F., Friedrich, Ulrike
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Association for Research in Vision and Ophthalmology 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718807/
https://ncbi.nlm.nih.gov/pubmed/33259607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.14.2
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