Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate

BACKGROUND: Protein synthesis is regulated by the availability of amino acids, the engagement of growth factor signaling pathways, and adenosine triphosphate (ATP) levels sufficient to support translation. Crosstalk between these inputs is extensive, yet other regulatory mechanisms remain to be char...

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Publicado en:Cancer Metab
Main Authors: Wilde, Blake R., Kaadige, Mohan R., Guillen, Katrin P., Butterfield, Andrew, Welm, Bryan E., Ayer, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718662/
https://ncbi.nlm.nih.gov/pubmed/33292639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-020-00233-6
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