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MondoA drives muscle lipid accumulation and insulin resistance

Obesity-related insulin resistance is associated with intramyocellular lipid accumulation in skeletal muscle. We hypothesized that contrary to current dogma, this linkage is related to an upstream mechanism that coordinately regulates both processes. We demonstrate that the muscle-enriched transcrip...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ahn, Byungyong, Wan, Shibiao, Jaiswal, Natasha, Vega, Rick B., Ayer, Donald E., Titchenell, Paul M., Han, Xianlin, Won, Kyoung Jae, Kelly, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693825/
https://ncbi.nlm.nih.gov/pubmed/31287806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129119
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