MondoA drives muscle lipid accumulation and insulin resistance

Obesity-related insulin resistance is associated with intramyocellular lipid accumulation in skeletal muscle. We hypothesized that contrary to current dogma, this linkage is related to an upstream mechanism that coordinately regulates both processes. We demonstrate that the muscle-enriched transcrip...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Ahn, Byungyong, Wan, Shibiao, Jaiswal, Natasha, Vega, Rick B., Ayer, Donald E., Titchenell, Paul M., Han, Xianlin, Won, Kyoung Jae, Kelly, Daniel P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693825/
https://ncbi.nlm.nih.gov/pubmed/31287806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129119
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