MondoA drives muscle lipid accumulation and insulin resistance

Obesity-related insulin resistance is associated with intramyocellular lipid accumulation in skeletal muscle. We hypothesized that contrary to current dogma, this linkage is related to an upstream mechanism that coordinately regulates both processes. We demonstrate that the muscle-enriched transcrip...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Ahn, Byungyong, Wan, Shibiao, Jaiswal, Natasha, Vega, Rick B., Ayer, Donald E., Titchenell, Paul M., Han, Xianlin, Won, Kyoung Jae, Kelly, Daniel P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693825/
https://ncbi.nlm.nih.gov/pubmed/31287806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129119
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