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MondoA drives muscle lipid accumulation and insulin resistance

Obesity-related insulin resistance is associated with intramyocellular lipid accumulation in skeletal muscle. We hypothesized that contrary to current dogma, this linkage is related to an upstream mechanism that coordinately regulates both processes. We demonstrate that the muscle-enriched transcrip...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Ahn, Byungyong, Wan, Shibiao, Jaiswal, Natasha, Vega, Rick B., Ayer, Donald E., Titchenell, Paul M., Han, Xianlin, Won, Kyoung Jae, Kelly, Daniel P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693825/
https://ncbi.nlm.nih.gov/pubmed/31287806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129119
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