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Nrf2 regulates interferon receptor expression and alters macrophage polarization in lupus

OBJECTIVE. Pristane-induced lupus is associated with nonresolving inflammation and deficiency of proresolving macrophages. Proresolving non-classical macrophages (NCM) are less responsive to type I interferon than classical (proinflammatory) macrophages (CM) reflecting their relative expression leve...

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Vydáno v:Arthritis Rheumatol
Hlavní autoři: Han, Shuhong, Zhuang, Haoyang, Lee, Pui Y., Li, Mingjia, Yang, Lijun, Nigrovic, Peter A., Reeves, Westley H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718430/
https://ncbi.nlm.nih.gov/pubmed/32500632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41383
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