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Differential responsiveness of monocyte and macrophage subsets to interferon

OBJECTIVE. Peripheral blood mononuclear cells (PBMC) from lupus patients exhibit a gene expression program (interferon signature) attributed to over-production of type I IFNs (IFN-I) by plasmacytoid dendritic cells. IFN-I were thought to play a role in the pathogenesis of lupus. This study examined...

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Bibliografische gegevens
Gepubliceerd in:Arthritis Rheumatol
Hoofdauteurs: Han, Shuhong, Zhuang, Haoyang, Lee, Pui Y., Li, Mingjia, Yang, Lijun, Nigrovic, Peter A., Reeves, Westley H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935410/
https://ncbi.nlm.nih.gov/pubmed/31390156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41072
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