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Inhibition of EZH2 enhances the antitumor efficacy of metformin in prostate cancer

Upregulation of EZH2 is associated with advanced stage and poor prognosis of PCa, it is therefore likely to be a promising therapeutic target. Metformin, a drug that has been used to treat type II diabetes, was found to have anti-neoplastic activity in different cancers. Herein, we report that the c...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Kong, Yifan, Zhang, Yanquan, Mao, Fengyi, Zhang, Zhuangzhuang, Li, Zhiguo, Wang, Ruixin, Liu, Jinghui, Liu, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718407/
https://ncbi.nlm.nih.gov/pubmed/33024029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0874
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