NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival

Although inflammation is necessary during the early phases of tissue repair, persistent inflammation contributes to fibrosis. Acute tendon injuries often heal through a fibrotic mechanism, which impedes regeneration and functional recovery. Because inflammation mediated by nuclear factor κB (NF-κB)...

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Pubblicato in:Sci Signal
Autori principali: Best, Katherine T., Nichols, Anne E.C., Knapp, Emma, Hammert, Warren C., Ketonis, Constantinos, Jonason, Jennifer H., Awad, Hani A., Loiselle, Alayna E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717665/
https://ncbi.nlm.nih.gov/pubmed/33203721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abb7209
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