Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis

Despite the requirement for Scleraxis-lineage (Scx(Lin)) cells during tendon development, the function of Scx(Lin) cells during adult tendon repair, post-natal growth, and adult homeostasis have not been defined. Therefore, we inducibly depleted Scx(Lin) cells (ScxLin(DTR)) prior to tendon injury an...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Best, Katherine T, Korcari, Antonion, Mora, Keshia E, Nichols, Anne EC, Muscat, Samantha N, Knapp, Emma, Buckley, Mark R, Loiselle, Alayna E
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Stem Cells and Regenerative Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850622/
https://ncbi.nlm.nih.gov/pubmed/33480357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62203
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