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Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing

Flexor tendon injuries heal with excessive scar tissue that limits range of motion and increases incidence of re-rupture. The molecular mechanisms that govern tendon healing are not well defined. Both the canonical nuclear factor kappa B (NF-κB) and mitogen activated protein kinase (MAPK) pathways h...

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Publicado no:Sci Rep
Main Authors: Best, Katherine T., Lee, Fredella K., Knapp, Emma, Awad, Hani A., Loiselle, Alayna E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662789/
https://ncbi.nlm.nih.gov/pubmed/31358843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47461-5
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